Research · Optizence

Research we publish with the failures included.

Each entry states what was tested, what would have counted as success before we looked, what did not work, and what the result cannot show. Where we can, we ship the interactive tool too.

Computational biology · Dengue

Which parts of the dengue envelope protein are worth testing as vaccine targets?

A residue-level model that scores the dengue envelope (E) protein for antibody targeting, tested against pre-registered criteria with every failure reported, plus an interactive atlas and a lab workbench for planning matched mutant experiments.

DengueEpitope rankingPre-registeredmRNA designInteractive

Computational hypotheses. Not validated in a laboratory.

Read the entryOpen the interactive Atlas